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The effects of house dust mite sublingual immunotherapy tablet on immunologic biomarkers and nasal allergen challenge symptoms.

Natasha C. Gunawardana,Qing Zhao,Leonidas N. Carayannopoulos,Kuenhi Tsai,Vladislav A Malkov,Diana Selverian,Graham Clarke,Tim Mant,Brent D. Butts,Kaare Lund,Trevor T. Hansel,Hendrik Nolte

Journal of Allergy and Clinical Immunology（2018）

Cited 10|Views37
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Abstract
Summary SQ HDM SLIT-tablet significantly increased serum HDM-specific IgG 4 and IgE blocking factor, and significantly decreased early phase nasal symptoms after nasal allergen challenge. No significant effects on cytokines or gene expression in nasal mucosa were observed.
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Key words
nasal allergen challenge symptoms,immunologic biomarkers,sublingual immunotherapy tablet,house dust
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