Nf2 mutation in Schwann cells delays functional neural recovery following injury.

•Nf2 mutation in Schwann cells (SCs) results in delayed neural recovery as measured by the Cat Walk.•Nf2 mutation in SCs results in reduced axon density but does not result in a significant reduction in axon regeneration.•Nf2 mutation in SCs results in a significant increase in extracellular matrix deposition.•Nf2 mutation in SCs does not result in a significant difference in conduction velocity or amplitude 90 days post-injury.