Instability of LDL particles predicts future cardiovascular deaths.

Maija Ruuth,Su Duy Nguyen,Terhi Vihervaara,Mika Hilvo,Teemu Daniel Laajala,Pradeep Kumar Kondadi,Gisterå Anton,Jenni Huusko,Matti Uusitupa,Ursula Schwab,Rudel Lawrence,Daniel Ketelhuth,Reijo Laaksonen,Marc Baumann,Tero Aittokallio, Matti Jauhiainen,Borén Jan,Kevin Jon Williams,Petri Kovanen,Katariina Öörni

Atherosclerosis（2017）

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摘要

Aim: Aggregation of LDL increases their retention within the arterial intima and induces foam cell formation thereby accelerating atherosclerosis. Nevertheless, the intrinsic susceptibility of human LDL to aggregate, defined here as LDL ‘instability’, has not been systematically evaluated.

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ldl particles

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