Fatty acid-binding protein 5 as a residual risk for atherosclerotic cardiovascular disease in patients with familial hypercholesterolemia.

Aim: Aim: Fatty acid-binding protein (FABP) 4 and FABP5 play important roles in the development of atherosclerosis and that their impacts differentially involve macrophages. We hypothesized FABPs may partly explain residual atherosclerotic cardiovascular disease (ASCVD) risk in statin-treated familial hypercholesterolemia (FH) patients. We investigated associations of plasma FABP4 and FABP5 levels with the presence of ASCVD and clinical features in these patients.