Independent Prognostic Significance of Monosomy 17 and Impact of Karyotype Complexity in Monosomal Karyotype/Complex Karyotype Acute Myeloid Leukemia: Results from Four ECOG-ACRIN Prospective Therapeutic Trials.

Stephen A Strickland,Zhuoxin Sun,Rhett P Ketterling,Athena M Cherry,Larry D Cripe,Gordon Dewald,Hugo F Fernandez,Gary A Hicks,Rodney R Higgins,Hillard M Lazarus,Mark R Litzow,Selina M Luger,Elisabeth M Paietta,Jacob M Rowe,Gail H Vance,Peter Wiernik,Anne E Wiktor,Yanming Zhang,Martin S Tallman

Leukemia Research（2017）

引用 18|浏览41

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摘要

•Prognostic impact of monosomal karyotype appears dependent on karyotype complexity.•Monosomy 5 lacks prognostic impact in context of AML with monosomal karyotype.•Monosomy 17 independently predicts for inferior survival among AML patients

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关键词

Myeloid Leukemia,Monosomal Karyotype,Complex Karyotype,Cytogenetics,Prognosis,Monosomy 17,Monosomy 5,Monosomy 7

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