Advances in Tissue-engineered Oral Mucosa

The large defect of oral and maxillofacial region doesn' t only affect the function and aesthetics but also has an adverse impact on patients' psychology.The traditional way to restore the defects are limited by donor site and secondary trauma.In recent years,the oral mucosal tissue engineering has developed rapidly and provides a new solution for craniofacial reconstruction.Tissue-engineered oral mucosa is an ideal substitute of oral mucosa.It can be used in clinical settings and in vitro experiments.This articles review the recent advances in tissue-engineered oral mucosa and its applications.