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Anti-Angiogenic Drug Loaded Liposomes: Nanotherapy For Early Atherosclerotic Lesions In Mice

Isabel Pont,Aracely Calatayud-Pascual,Alicia López-Castellano, Elena P Albelda,Enrique García-España, Luis Martí-Bonmatí,Juan C Frias,M Teresa Albelda

PLOS ONE（2018）

Cited 9|Views13
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Abstract
Fumagillin-loaded liposomes were injected into ApoE-KO mice. The animals were divided into several groups to test the efficacy of this anti-angiogenic drug for early treatment of atherosclerotic lesions. Statistical analysis of the lesions revealed a decrease in the lesion size after 5 weeks of treatment.
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Key words
liposomes,nanotherapy,early atherosclerotic lesions,anti-angiogenic
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