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Immunization of mice with egG1Y162-1/2 provides protection against Echinococcus granulosus infection in BALB/c mice.

Fengbo Zhang,Shaoyu Li,Yuejie Zhu,Chuntao Zhang,Yujiao Li,Haimei Ma,Nannan Pang,Mengting An,Hongying Wang,Jianbing Ding

Molecular Immunology（2018）

Cited 13|Views24
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Abstract
•T-B combined epitopes of egG1Y162 antigen are predicted.•EgG1Y162-1/2 protein is expressed and purified in vitro.•The IgG levels in serum are increased after EgG1Y162-1/2 immunization.•egG1Y162-1/2 enhances protective immunity in mice.
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Key words
EgG1Y162 antigen,Bioinformatics,T-B combined epitopes,Prokaryotic expression
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