Translation And Validation Of The 15-Item Myasthenia Gravis Quality Of Life Scale In Dutch

Introduction: The 15-item Myasthenia Gravis Quality of Life (MG-QOL15) scale has been developed to assess the health-related quality of life of patients with myasthenia gravis (MG). The aim of this study was to translate the original English version into Dutch and to test the test-retest reliability and construct validity. Methods: Fifty patients with MG were included. Test-retest reliability and internal consistency were assessed using the intraclass correlation coefficient (ICC) and the Cronbach alpha. Construct validity was assessed by testing 5 predefined hypotheses. Results: A good test-retest reliability was confirmed with an ICC of 0.866. The Cronbach a was 0.93. The predefined hypotheses were confirmed in 80% of cases, which points to good construct validity. Discussion: The Dutch MG-QOL15 has good test-retest reliability and good construct validity. It can be used for research in a Dutch-speaking population. It is also suitable for monitoring individual patients in clinical practice.