Nandrolone combined with strenuous resistance training reduces vascular nitric oxide bioavailability and impairs endothelium-dependent vasodilation.

Vinicius Guzzoni,Tatiana Sousa Cunha,Vander José das Neves, Larissa Briet,Rafaela Costa,Maria José Costa Sampaio Moura,Vanessa Oliveira,Maria do Carmo Pinho Franco,Pedro Duarte Novaes,Fernanda Klein Marcondes

Steroids（2018）

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摘要

•Nandrolone plus strenuous RT impairs acetylcholine-mediated aorta vasodilation.•Nandrolone plus strenuous RT increased reactive species of oxygen levels.•Nandrolone plus strenuous RT dramatically reduced vascular NO bioavailability.•Nandrolone plus strenuous RT increased arterial wall thickness.•Combination of nandrolone and strenuous RT might lead endothelial dysfunction.

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关键词

Nandrolone,Resistance training,Vasodilatation,Nitric oxide,Reactive oxygen species

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