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Interactions among Variants in Eicosanoid Genes Increase Risk of Atherothrombotic Stroke in Chinese Populations.

Xingyang Yi, Jing Lin,Chun Wang,Ruyue Huang,Yingying Liu

Journal of Stroke and Cerebrovascular Diseases（2017）

Cited 4|Views5
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Abstract
PTGS2 rs20417, PTGIS rs5602, and TBXAS1 rs41708 three-locus interactions may confer a higher risk for atherothrombotic stroke. The combinatorial analysis used in this study may be helpful to elucidate complex genetic risk for IS.
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Key words
Ischemic stroke,genetic polymorphism,eicosanoic acids,genetic variation,generalized multifactor dimensionality reduction
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