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X-linked carriers of chronic granulomatous disease: Illness, lyonization, and stability.

Beatriz E Marciano,Christa S Zerbe,E Liana Falcone,Li Ding,Suk See DeRavin,Janine Daub,Samantha Kreuzburg,Lynne Yockey,Sally Hunsberger, Ladan Foruraghi,Lisa A Barnhart,Kabir Matharu,Victoria Anderson,Dirk N Darnell,Cathleen Frein,Danielle L Fink,Karen P Lau,Debra A Long Priel,John I Gallin,Harry L Malech,Gulbu Uzel,Alexandra F Freeman,Douglas B Kuhns,Sergio D Rosenzweig,Steven M Holland

Journal of Allergy and Clinical Immunology（2018）

Cited 136|Views65
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Abstract
A low %DHR value strongly predicts infection risk in X-linked CGD carriers, and the carrier state itself is associated with autoimmunity.
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Key words
Superoxide,X inactivation,dihydrorhodamine flow cytometry test,autoimmunity,lyonization
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