Structural snapshot of cytoplasmic pre-60S ribosomal particles bound by Nmd3, Lsg1, Tif6 and Reh1

Chengying Ma,Shan Wu,Ningning Li,Yan Chen,Kaige Yan,Zhifei Li,Lvqin Zheng,Jianlin Lei,John L Woolford Jr,Ning Gao

NATURE STRUCTURAL & MOLECULAR BIOLOGY（2017）

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摘要

The cryo-EM structure of pre-60S purified via Nmd3 provides molecular insights into the roles of assembly factors Nmd3, Lsg1, Tif6 and Reh1 in the last steps of ribosomal large-subunit maturation.

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关键词

Cryoelectron microscopy,Ribosome,Life Sciences,general,Biochemistry,Protein Structure,Membrane Biology,Biological Microscopy

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