Increased expression of negative regulators of cytokine signaling during chronic HIV disease cause functionally exhausted state of dendritic cells.

Meenakshi Sachdeva,Aman Sharma,Sunil K Arora

Cytokine（2017）

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摘要

•Dysfuctional DC during HIV infection have far reaching consequences.•DC os HIV-1 infected patients depict functional exhaustion.•Upregulated expression of negative regulatory factors lead to exhausted state of DCs.

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关键词

HIV,Dendritic cells,Negative regulators of cytokine signaling,Exhaustion

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