PFOA-induced metabolism disturbance and multi-generational reproductive toxicity in Oryzias latipes.

Jin Wuk Lee,Jae-Woo Lee,Kyungtae Kim,Yu-Jin Shin,Jieun Kim,Suhkmann Kim,Heejung Kim,Pilje Kim,Kyunghwa Park

Journal of Hazardous Materials（2017）

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摘要

•PFOA can affect carbohydrate metabolism and osmoregulation of Oryzias latipes.•Glucose content can be used as a biomarker for PFOA exposure in Oryzias latipes.•PFOA caused histological abnormality in gonad and thyroid follicular cell.•PFOA caused multi-generational reproductive toxicity in Oryzias latipes.

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关键词

Perfluorooctanoic acid,Oryzias latipes,Multi-generational reproductive toxicity,Metabolism disturbance

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