Stimulated Raman scattering of polymer nanoparticles for multiplexed live-cell imaging.
CHEMICAL COMMUNICATIONS(2017)
Abstract
A novel nanoparticle-based imaging strategy is introduced that couples biocompatible organic nanoparticles and stimulated Raman scattering (SRS) microscopy. Polymer nanoparticles with vibrational labels incorporated were readily prepared for multi-color SRS imaging with excellent photo-stability. The Raman-active polymer dots are nontoxic, rapidly enter various cell types, and are applied in multiplexed cell-type sorting.
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Key words
polymer nanoparticles,imaging,live-cell
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