Gelatin- and starch-based hydrogels. Part B: In vitro mesenchymal stem cell behavior on the hydrogels.
Carbohydrate Polymers(2017)
Abstract
•Evaluation of the in vitro response of MSC to hydrogels with varying chemical composition (i.e. starch/gelatin ratio, methacrylation degree).•The gelatin- and starch-based hydrogels exhibited no adverse effect on viability of the MSC cultured on them.•On the least crosslinked and thus most flexible hydrogels, the highest degree of adipogenic differentiation of MSC was found.•Osteogenic differentiation of MSC was the strongest on the most rigid, starch-blended hydrogels.•Gelatin-based hydrogels can be optimized regarding maximum promotion of either adipogenic or osteogenic MSC differentiation in vitro.
MoreTranslated text
Key words
Gelatin,Starch,Hydrogel,Mesenchymal stem cells (MSC),Viability,Proliferation,Adipogenic differentiation,Osteogenic differentiation,Tissue engineering
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined