Copper(I)-catalysed oxidative C-N coupling of 2-aminopyridine with terminal alkynes featuring a C C bond cleavage promoted by visible light

Facile visible-light promoted copper-catalyzed aerobic oxidative C-N coupling between 2-aminopyridine and terminal alkynes at room temperature via C C triple bond cleavage is described. This reaction allows direct synthesis of biologically important pyridyl amides by utilization of commercially available starting materials without the need for bases/external oxidants.