Reversible regulation of the supramolecular chirality of a cyanine dye by using the G-quadruplex structure as a template.

Multiple cycle regulation of the supramolecular chirality of a cyanine dye has been successfully achieved by using DNA G-quadruplexes as templates, which is easily controllable by repeated addition of Ag+ and cysteine (Cys). This work provides an easy and controllable strategy for the chiral regulation of supramolecules.