HOXA9 transcriptionally regulates the EPHB4 receptor to modulate trophoblast migration and invasion.

Xiaoping Liu,Xiaoxia Liu,Weifang Liu,Minglian Luo,Hui Tao,Di Wu,Yin Zhao,Li Zou

Placenta（2017）

引用 8|浏览7

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摘要

•HOXA9 and EPHB4 expression increased in preeclamptic placenta compared with normal controls.•HOXA9 inhibited cells migration and invasion by facilitating EPHB4 expression in HTR-8/SVneo cells.•HOXA9 could transcriptionally activate EPHB4 expression in HTR-8/SVneo.

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关键词

HOXA9,EPHB4,Transcriptional regulation,Trophoblast,Preeclampsia

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