Plasma ferritin concentrations are not associated with abdominal aortic aneurysm diagnosis, size or growth.
Atherosclerosis(2016)
摘要
•There is no current medical treatment to slow abdominal aortic aneurysm (AAA) growth.•Recent animal data have suggested that an iron-reduced diet protects against AAA formation, suggesting that i) total body iron overload may be involved in AAA pathogenesis. ii) reduction of iron may be a treatment for AAA. Here, we assessed whether total body iron overload as assessed by circulating ferritin concentration was associated with AAA presence, size and growth in a large cohort of community-screened men.•Our data demonstrate no relationship between serum ferritin and AAA and do not support iron reduction as a therapy for AAA.
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关键词
Abdominal aortic aneurysm,Ferritin,Iron overload,Biomarker
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