Plasma ferritin concentrations are not associated with abdominal aortic aneurysm diagnosis, size or growth.

Atherosclerosis(2016)

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摘要
•There is no current medical treatment to slow abdominal aortic aneurysm (AAA) growth.•Recent animal data have suggested that an iron-reduced diet protects against AAA formation, suggesting that i) total body iron overload may be involved in AAA pathogenesis. ii) reduction of iron may be a treatment for AAA. Here, we assessed whether total body iron overload as assessed by circulating ferritin concentration was associated with AAA presence, size and growth in a large cohort of community-screened men.•Our data demonstrate no relationship between serum ferritin and AAA and do not support iron reduction as a therapy for AAA.
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关键词
Abdominal aortic aneurysm,Ferritin,Iron overload,Biomarker
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