Bone marrow mesenchymal stromal cells alleviate brain white matter injury via the enhanced proliferation of oligodendrocyte progenitor cells in focal cerebral ischemic rats.

Xiaohe Yu,Hongjuan Wu,Yansong Zhao, Yuanyuan Guo,Yuxi Chen,Peng Dong,Qingjie Mu,Xin Wang,Xiaoli Wang

Brain Research（2018）

引用 15|浏览7

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摘要

•BMSCs could alleviate the white matter injury in focal cerebral ischemic rats.•The effects of BMSCs on white matter injury could be monitored by MRI in vivo.•The alleviation of brain white matter injury is correlated with proliferating OPCs.

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关键词

BMSCs,BrdU,DTI,DTT,FI,MCAO,MRI,Shh,T2WI,OPCs,MBP,NF-H,NS

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