Vitamin D receptor gene polymorphisms, smoking, and risk of sporadic Parkinson's disease in Japan.

Keiko Tanaka,Yoshihiro Miyake,Wakaba Fukushima,Chikako Kiyohara,Satoshi Sasaki,Yoshio Tsuboi,Tomoko Oeda,Hiroyuki Shimada,Nobutoshi Kawamura,Nobutaka Sakae,Hidenao Fukuyama,Yoshio Hirota,Masaki Nagai,Yoshikazu Nakamura

Neuroscience Letters（2017）

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摘要

•Polymorphism of FokI may be associated with the risk of Parkinson’s disease.•No relationships were observed between TaqI, ApaI, or BsmI and Parkinson’s disease.•VDR haplotypes inferred were not associated with Parkinson’s disease.•Smoking did not modify the association between FokI and Parkinson’s disease.

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关键词

Case-control study,Gene-environment interaction,Japanese,Parkinson’s disease,Smoking,VDR polymorphisms

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