Xylan-based temperature/pH sensitive hydrogels for drug controlled release.

Cundian Gao,Junli Ren,Cui Zhao,Weiqing Kong,Qingqing Dai,Qifeng Chen,Chuanfu Liu,Runcang Sun

Carbohydrate Polymers（2016）

引用 103|浏览17

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摘要

•Xylan-based P(NIPAm-co-AA) hydrogels were prepared.•These hydrogels were temperature/pH sensitive and biocompatible.•LCST of hydrogels was at 34°C and increased with increasing the AA content.•The drug cumulative release rate was 90% and 26% in intestinal and gastric fluids.•They could be used as drug carriers for intestinal-targeted oral drug delivery.

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关键词

Xylan,Hydrogels,Temperature/pH sensitivity,Drug release,Biocompatibility

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