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Structure of the 40S–ABCE1 post-splitting complex in ribosome recycling and translation initiation

André Heuer,Milan Gerovac,Christian Schmidt,Simon Trowitzsch,Anne Preis,Peter Kötter,Otto Berninghausen,Thomas Becker,Roland Beckmann,Robert Tampé

NATURE STRUCTURAL & MOLECULAR BIOLOGY（2017）

Cited 75|Views26
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Abstract
Cryo-EM structures of the yeast 40S in complex with ribosome-splitting protein ABCE1, along with functional analyses, reveal that the FeS cluster domain undergoes a 150° rotation to dissociate ribosomal subunits.
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Key words
Cryoelectron microscopy,Ribosome,Supramolecular assembly,Life Sciences,general,Biochemistry,Protein Structure,Membrane Biology,Biological Microscopy
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