Dynamics of APC recruitment at the site of injection following injection of vaccine adjuvants.

Vaccine(2017)

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摘要
•Intramuscular adjuvant injection induces adjuvant-specific cell influx in muscle.•Adjuvants induce a transient pro-inflammatory milieu in muscle.•The capacity of muscle APC to load and present antigen is affected by the adjuvant.
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关键词
APC,CFA,CFSE,CL,DC,DDA,dLN,hPG,hpi,i.m.,IL,LPS,MPL,PAM,SOI,TDB,TDM,TNF-α
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