Exploring Overlaps Between the Genomic and Environmental Determinants of LVH and Stroke: A Multicenter Study in West Africa.

Abiodun M Adeoye,Bruce Ovbiagele,Philip Kolo,Lambert Appiah,Akinyemi Aje,Oladimeji Adebayo,Fred Sarfo,Joshua Akinyemi,Gregory Adekunle,Francis Agyekum,Vincent Shidali,Okechukwu Ogah,Dan Lackland,Mulugeta Gebregziabher,Donna Arnett,Hemant K Tiwari,Rufus Akinyemi, Ojo Olakanmi Olagoke,Ayodipupo Sikiru Oguntade,Taiwo Olunuga,Kelechi Uwanruochi,Carolyn Jenkins, Patrick Adadey,Henry Iheonye,Lukman Owolabi,Reginald Obiako,Samuel Akinjopo,Kevin Armstrong,Albert Akpalu,Adekunle Fakunle,Raelle Saulson,Mayowa Aridegbe,Paul Olowoyo,Godwin Osaigbovo,Josephine Akpalu,Bimbo Fawale,Philip Adebayo,Oyedunni Arulogun,Philip Ibinaiye,Atinuke Agunloye,Naser Ishaq,Kolawole Wahab,Onoja Akpa,Omisore Adeleye, Andrew Bock-Oruma,Godwin Ogbole,Sylvia Melikam,Joseph Yaria,Luqman Ogunjimi,Abdul Salaam,Taofiki Sunmonu,Akintomiwa Makanjuola,Temitope Farombi,Ruth Laryea,Ezinne Uvere,Salaam Kehinde,Innocent Chukwuonye,Paschal Azuh,Morenikeji Komolafe,Adeseye Akintunde,Olugbo Obiabo,Olusegun Areo,Issa Kehinde,Adeniyi G Amusa,Mayowa Owolabi

Global Heart（2017）

Cited 11|Views37

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Abstract

•Left ventricular hypertrophy (LVH) was found in more than one-half of stroke patients in Africa.•LVH was more common in younger patients, suggesting a genetic component.•Hypertension was a major modifiable risk factor for stroke as well as LVH.•SIREN will elucidate polygenic overlap between LVH and stroke among Africans.

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Key words

stroke,lvh,genomic

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