Evaluating the Four Kallikrein Panel of the 4Kscore for Prediction of High-grade Prostate Cancer in Men in the Canary Prostate Active Surveillance Study.

Daniel W Lin,Lisa F Newcomb,Marshall D Brown,Daniel D Sjoberg,Yan Dong,James D Brooks,Peter R Carroll,Matthew Cooperberg,Atreya Dash,William J Ellis,Michael Fabrizio,Martin E Gleave,Todd M Morgan,Peter S Nelson,Ian M Thompson,Andrew A Wagner,Yingye Zheng

European Urology（2017）

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摘要

In men undergoing active surveillance, the Four Kallikrein panel provides incremental value over routine clinical information for prediction of high-grade cancer in the first biopsy after diagnosis. These data support incorporation of emerging biomarkers in models that aid in patient decision-making.

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关键词

Prostatic neoplasms,Prospective studies,Active surveillance,Biomarker,Kallikrein

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