Low-Dose Anti-Thymocyte Globulin for Graft-Versus-Host-Disease Prophylaxis in Matched Unrelated Allogeneic Hematopoietic Stem Cell Transplant

Adam Bryant,Ranjeeta Mallick,Lothar B. Huebsch,David S. Allan,Harold Atkins,Grizel Anstee,Isabelle Bence-Bruckler,Linda Hamelin,Michael Hodgins,Mitchell Sabloff,Nicholas Scrivens,Dawn C. Maze,Christopher N. Bredeson,Natasha Kekre

Biology of Blood and Marrow Transplantation（2017）

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摘要

•Low-dose Thymoglobulin leads to low rates of GVHD in matched unrelated donor HCT.•Low-dose Thymoglobulin leads to less GVHD than in unexposed related donor HCT.•Thymoglobulin in GVHD prophylaxis does not increase relapse or infection rates.

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关键词

Graft-versus-host disease,Antithymocyte globulin,Matched unrelated donor allogeneic hematopoietic stem cell transplantation

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