Synthesis of novel C-9 carbon substituted derivatives of artemisinin.

Daniel Meyer,Toni Smeilus,Dimanthi Pliatsika,Farnoush Mousavizadeh,Athanassios Giannis

Bioorganic & Medicinal Chemistry（2017）

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摘要

Several artemisinin derivatives carrying several groups (alkyl, hydroxyalkyl, allyl or azide) at position 9 have been synthesized starting from artemisinin via enolate formation and subsequent reaction with appropriate electrophiles.

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关键词

Artemisinin,Anticancer,Antimalarial

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