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Prognosis biomarkers evaluation in chronic lymphocytic leukemia.

Lorena Caixeta Gomes,Fernanda Cristina Gontijo Evangelista,Lirlândia Pires de Sousa,Sergio Schusterschitz da Silva Araujo,Maria das Graças Carvalho,Adriano de Paula Sabino

Hematology/Oncology and Stem Cell Therapy（2017）

Cited 6|Views19
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Abstract
ZAP-70 gene expression was not detected as a discriminant biomarker in these CLL patients. An imbalance between apoptosis-related proteins was observed in the present study, corroborating the hypothesis of increased survival of lymphocytes in CLL patients.
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Key words
Apoptosis/survival proteins,Chronic lymphocytic leukemia,ZAP-70
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