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Hydrogen sulfide protects against TNF-α induced neuronal cell apoptosis through miR-485-5p/TRADD signaling.

Zhiqiang Chen,Zhonghe Zhang,Dongdong Zhang,Hao Li,Zhongye Sun

Biochemical and Biophysical Research Communications（2016）

Cited 30|Views3
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Abstract
•H2S suppresses serum TNF-α production in patients with spinal cord I/R injury.•miR-485-5p was downregulated in patient with spinal cord I/R injury.•miR-485-5p directly regulates TRADD expression in neural cells.•H2S protect against TNF-α triggered neural cell apoptosis via miR-485-5p/TRADD.
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Hydrogen sulfide,miR-485-5p,TRADD,AGE1.HN,SY-SH-5Y
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