BRANE Clust: Cluster-Assisted Gene Regulatory Network Inference Refinement
IEEE/ACM Transactions on Computational Biology and Bioinformatics(2018)
摘要
Discovering meaningful gene interactions is crucial for the identification of novel regulatory processes in cells. Building accurately the related graphs remains challenging due to the large number of possible solutions from available data. Nonetheless, enforcing a priori on the graph structure, such as modularity, may reduce network indeterminacy issues. BRANE Clust (BiologicallyRelated A priori ...
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关键词
Optimization,Labeling,Biological information theory,Graphical models,Probabilistic logic,Merging,Databases
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