Extracting Stage-Specific and Dynamic Modules Through Analyzing Multiple Networks Associated with Cancer Progression.

Xiaoke Ma,Wanxin Tang,Peizhuo Wang,Xingli Guo,Lin Gao

IEEE/ACM Transactions on Computational Biology and Bioinformatics（2018）

Cited 24|Views24

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Abstract

Determining the dynamics of pathways associated with cancer progression is critical for understanding the etiology of diseases. Advances in biological technology have facilitated the simultaneous genomic profiling of multiple patients at different clinical stages, thus generating the dynamic genomic data for cancers. Such data provide enable investigation of the dynamics of related pathways. Howev...

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Key words

Heuristic algorithms,Genomics,Bioinformatics,Breast cancer,Gene expression

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