Biopharmaceutical evaluation of epigallocatechin gallate-loaded cationic lipid nanoparticles (EGCG-LNs): In vivo, in vitro and ex vivo studies

Joana F. Fangueiro,Ana C. Calpena,Beatriz Clares,Tatiana Andreani,Maria A. Egea,Francisco J. Veiga,Maria L. Garcia,Amélia M. Silva,Eliana B. Souto

International Journal of Pharmaceutics（2016）

引用 106|浏览7

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摘要

Transcorneal permeation profile of EGCG-CTAB LNs (■) and EGCG-DDAB LNs (♦), and respective stereomicrographs of the CAM after 5min of exposure to lipid nanoparticles.

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关键词

Draize test,HET-CAM test,Epigallocatechin gallate,Lipid nanoparticles,Ocular delivery

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