Muscarinic cholinergic receptor antagonists in the VTA and RMTg have opposite effects on morphine-induced locomotion in mice

Stephan Steidl,Ekamjeet S. Dhillon, Natasha Sharma,Jessica Ludwig

Behavioural Brain Research（2017）

引用 16|浏览9

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摘要

•VTA or RMTg morphine each increase locomotion.•VTA atropine blocks VTA morphine locomotion.•RMTg atropine increases RMTg morphine locomotion.•RMTg M3 but not M4 receptors are critical for RMTg morphine locomotion.

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关键词

Laterodorsal tegmental nucleus,Pedunculopontine tegmental nucleus,Opiates,Dopamine,Acetylcholine

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