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The atypical antipsychotic blonanserin reverses (+)-PD-128907- and ketamine-induced deficit in executive function in common marmosets

Manato Kotani,Takeshi Enomoto,Takeshi Murai,Tomokazu Nakako,Yoshihiro Iwamura,Akihiko Kiyoshi,Kenji Matsumoto,Atsushi Matsumoto,Masaru Ikejiri,Tatsuo Nakayama,Yuji Ogi,Kazuhito Ikeda

Behavioural Brain Research（2016）

Cited 13|Views16
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Abstract
•The dopamine D3 receptor-preferring agonist (+)-PD-128907 impairs marmosets executive function.•Blonanserin reverses (+)-PD-128907-induced deficit in executive function.•The NMDA receptor antagonist ketamine impairs marmosets executive function.•Blonanserin reverses ketamine-induced deficit in executive function.
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Key words
Common marmoset,Schizophrenia,Object retrieval with detour (ORD) task,Blonanserin,Dopamine D3 receptor,Ketamine
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