2D-gel based proteomics unravels neurogenesis and energetic metabolism dysfunction of the olfactory bulb in CUMS rat model

Behavioural Brain Research(2016)

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摘要
•Using 2-D gel electrophoresis coupled with mass spectrometry to characterize the Olfactory Bulb under CUMS treatment.•29 out of 47 differential proteins were identified.•7 differential proteins were ruled out to validate guided by KEGG and IPA biological analysis.•Global proteomics Characterization of OB may unravel the dysfunction under CUMS treatment.
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关键词
OB,CUMS,MDD,2-DE
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