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Sequential extraction of bioactive compounds from Melia azedarach L. in fixed bed extractor using CO2, ethanol and water

Raphaela G. Bitencourt,Carmen Lucia Queiroga,Gustavo H.B. Duarte, Marcos N. Eberlin,Luciana K. Kohn,Clarice Weis Arns,Fernando A. Cabral

The Journal of Supercritical Fluids（2014）

Cited 21|Views10
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Abstract
•Sequential extraction was carried out in four steps using scCO2, scCO2/ethanol mixture, ethanol and ethanol/water mixture.•The 1st step extract with scCO2 showed inhibition against HSV-1 Virus.•The 2nd step extract showed ability to reduce the surface tension and inhibition against HSV-1 Virus.
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Key words
Melia azedarach L.,Sequencial extraction,Supercritical extraction,Bioactive compounds,Saponins,Antiviral activity
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