Preparation and characterization of naringenin microparticles via a supercritical anti-Solvent process
The Journal of Supercritical Fluids（2018）
Abstract
•NAR microparticles were prepared by SEDS with a mixed solvent of acetone and DCM.•Chemical or crystal structures of NAR did not change during SEDS processing.•NAR particles changed to small flakes with smooth surfaces during SEDS processing.•Micronized NAR microparticles have higher dissolution rate than raw NAR.
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Key words
Naringenin,Supercritical CO2,Microparticles,SEDS,Dissolution rate
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