High-throughput sequencing reveals novel features of immunoglobulin gene rearrangements in Burkitt lymphoma

Katharine A Lombardo,David G Coffey,Alicia J Morales,Christopher S Carlson,Andrea M H Towlerton,Sarah E Gerdts,Francis K Nkrumah,Janet Neequaye,Robert J Biggar,Jackson Orem,Corey Casper,Sam M Mbulaiteye,Kishor G Bhatia,Edus H Warren

Blood Advances（2017）

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摘要

TO THE EDITOR:We thank Ralf Kuppers for his interest in our article[1][1] and for his thoughtful commentary.[2][2] We address each of the points he raises below.First, Kuppers claims that, in contrast to what has been demonstrated in mice,[3][3] not all normal human B-cell progenitors undergo

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immunoglobulin gene rearrangements,burkitt lymphoma,high-throughput

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