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Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-b]Pyridazine- Based P38 MAP Kinase Inhibitors

Akira Kaieda,Masashi Takahashi,Takafumi Takai,Masayuki Goto,Takahiro Miyazaki,Yuri Hori,Satoko Unno,Tomohiro Kawamoto,Toshimasa Tanaka,Sachiko Itono,Terufumi Takagi,Teruki Hamada,Mikio Shirasaki,Kengo Okada,Gyorgy Snell, Ken Bragstad,Bi-Ching Sang,Osamu Uchikawa,Seiji Miwatashi

Bioorganic & Medicinal Chemistry（2017）

Cited 16|Views4
Key words
P38 mitogen-activated protein kinase inhibitors,Rheumatoid arthritis,Structure-based design,Imidazo[1,2-b]pyridazine derivatives,Pyridine N-oxide
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