Changing sero-epidemiology of hepatitis A in Asia Pacific countries: A systematic review.

•Hepatitis A severity increases with age, and immunity is life-long.•Decreased endemicity could result in increased age and severity of cases.•The Asian literature shows increasing age at first exposure, suggesting a transition in endemicity.•Extensive gaps in the literature were identified for some countries.•The public health impacts of this changing epidemiological context should be examined.