Evaluation of Chimerism Dynamics after Allogeneic Hematopoietic Stem Cell Transplantation in Children with Non-Malignant Diseases.

Maura Faraci,Francesca Bagnasco,Massimiliano Leoni,Stefano Giardino,Paola Terranova,Lorenzo Subissi,Marco Di Duca,Daniela Di Martino,Edoardo Lanino

Biology of Blood and Marrow Transplantation（2018）

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摘要

•Evaluation of chimerism is crucial after HSCT performed for nonmalignant diseases.•Acute and chronic GVHD promote CC in patients with nonmalignant diseases.•RIC regimen is associated with mixed chimerism.•Strict chimerism monitoring identifies early diagnosis of chimerism evolution.

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关键词

Chimerism,Nonmalignant disease,Graft-versus-host disease,Bone marrow transplantation

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