Mouse β-defensin-14 for inducing the maturation of dendritic cells.
International Immunopharmacology(2018)
Abstract
•Animal air pouch model was established to further evidence the results of in vitro experiments.•Mouse β-defensin-14 can promote dendritic cell maturation but does not aggravate inflammation like LPS.•The mechanism of dendritic cell maturation induced by mouse β-defensin-14 may involve TLR-4.
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Key words
Antimicrobial peptide,Mouse β-defensin-14,Dendritic cell,Immune regulation
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