Antibacterial Effect Of 2r,3r-Dihydromyricetin On The Cellular Functions Of Staphylococcus Aureus

The C-3-OH, C-4 carbonyl oxygen and hydrogenation of C2=C3 bond on the C-ring of 2R,3R-dihydromyricetin (DMY) proved to be not necessary for the antibacterial activity against Staphylococcus aureus. DMY significantly decreased the intracellular ATP of S. aureus cells but had few effects on pH(in), proline oxidation, succinate dehydrogenase activity or malate dehydrogenase activity.