Effects and Mechanisms of matrix metalloproteinase2 on neural differentiation of induced pluripotent stem cells.

Tao Shu,Chang Liu,Mao Pang,Juan Wang,Bin Liu,Wei Zhou,Xuan Wang,Tao Wu,Qiyou Wang,Limin Rong

Brain Research（2018）

引用 11|浏览21

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摘要

•MMP2 promoted the neural differentiation of iPSCs.•MMP2 siRNA decreased the differentiation of iPSCs to neural lineages.•These processes were modulated by AKT signaling pathway.

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关键词

Induced pluripotent stem cells,Matrix metalloproteinases,Neuronal differentiation,Neural stem cells,AKT

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