Raman spectroscopy as a PAT for pharmaceutical blending: Advantages and disadvantages.

Daniela Riolo,Alessandro Piazza, Ciro Cottini, Margherita Serafini, Emilio Lutero, Erika Cuoghi, Lorena Gasparini, Debora Botturi,Iari Gabriel Marino,Irene Aliatis,Danilo Bersani,Pier Paolo Lottici

Journal of Pharmaceutical and Biomedical Analysis（2018）

引用 28|浏览10

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摘要

•Powder homogeneity is monitored by Raman spectroscopy in real case conditions.•Raman technique allows the measurement of multi-component blends.•Raman spectroscopy is compared with the most traditional HPLC analysis.

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关键词

Raman spectroscopy,High performance liquid chromatography (HPLC),Process analytical technologies (PAT),Powder blending processes,Pharmaceuticals

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