SATB1 and bladder cancer: Is there a functional link?

Dharamainder Choudhary,Jessica M Clement,Shilpa Choudhary,Olga Voznesensky,Carol C Pilbeam,Benjamin L Woolbright,John A Taylor

Urologic Oncology: Seminars and Original Investigations（2018）

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摘要

•SATB1, a global transcription regulator, is overexpressed in bladder cancer cell lines.•Functional assessment resulted in conflicting findings in different cell lines.•Given inconsistency of findings, the role of SATB1 in bladder cancer is unclear at this time.

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关键词

Urothelial carcinoma,Chemoresistance,Cisplatin,Oncomine,Laser-capture microdissection,Apoptosis

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