Brewer's yeast is a potent inducer of fever, sickness behavior and inflammation within the brain.

R Dangarembizi,K H Erlwanger,C Rummel,J Roth,M T Madziva,L M Harden

Brain, Behavior, and Immunity（2018）

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摘要

•Saccharomyces cerevisiae (Brewer’s yeast) induces fever, lethargy and anorexia.•Brewer’s yeast induces release of pro-inflammatory cytokines in the blood and brain.•Brewer’s yeast activates STAT-3, NF-κB, and NF-IL6 in the brain.•Brewer’s yeast increases hypothalamic expression of cyclooxygenase-2.

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关键词

COX,DAPI,EDTA,IκBα,LPS,MnPO,mPGES,MULV,NF-κB,NF,OVLT,IL,PG,RT PCR,STAT-3,SOCS-3,TNF,NDS,vWF

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